5H-Pyrimido[5,4-b]indole, 4-chloro-8-fluoro- - Names and Identifiers
5H-Pyrimido[5,4-b]indole, 4-chloro-8-fluoro- - Physico-chemical Properties
Molecular Formula | C10H5ClFN3
|
Molar Mass | 221.62 |
Density | 1.599±0.06 g/cm3(Predicted) |
Boling Point | 419.7±40.0 °C(Predicted) |
pKa | 11.48±0.30(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD00753478 |
5H-Pyrimido[5,4-b]indole, 4-chloro-8-fluoro- - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
5H-Pyrimido[5,4-b]indole, 4-chloro-8-fluoro- - Introduction
[5,4-b]indole is an organic compound with the formula C11H5ClFN2. The following is a description of its nature, use, formulation and safety information:
Nature:
-[5,4-b]indole is a solid, white crystal at room temperature.
-Its melting point at normal pressure is about 250-252°C.
-In solvents, it can be dissolved in strongly polar solvents such as dimethyl sulfoxide and dimethylformamide, but it has poor solubility in non-polar solvents.
-This compound is stable in the air, but will gradually decompose in the sun.
Use:
-[5,4-b]indole can be used as an intermediate in organic synthesis to prepare biologically active compounds.
-It can also be used for research and development in the field of medicine, such as drug synthesis and efficacy evaluation.
Preparation Method:
-[5,4-b]indole can be synthesized by a synthetic route.
-A commonly used synthesis method is to obtain its precursor compound through a nucleophilic substitution reaction of 2,2,3,3-tetrafluorophenyl 4-chloroacetone, and then prepare the target compound through a ring-closing reaction.
Safety Information:
-[5,4-b]indole has limited safety information and needs to be handled and stored properly.
-Due to its chemical properties, it may be harmful to the human body and the environment, so you need to pay attention to safety measures during use.
-When operating, you should wear appropriate personal protective equipment, such as laboratory gloves, goggles and protective clothing.
-When storing, it should be stored in a sealed container, away from fire and oxidizing agents.
Last Update:2024-04-09 19:06:01